Charmed/Tear Jerker

Charmed is notorious for being full of Narm, the fourth-season's "Hell Hath No Fury" as fury-Piper screams at the top of her lungs "How dare you leave me?!" to Prue's grave is sad. Considering how cheap death usually is for the Halliwell sisters, this kind of permanence in the show isn't taken lightly.
- Even the cheap deaths can be devastating when they're played well. The fact that she's alive again by the next episode doesn't make Piper's "...Prue? I'm cold..." in All Hell Breaks Loose any less soul-crushing.
In "Morality Bites" when Phoebe realises that she must die for her crimes and Prue and Piper have to stand back and watch her burn to death.
Prue's funeral at the start of season 4. The music adds to it as well, Holly Marie Combs as usual is brilliant in that scene and Darryl the Deadpan Snarker was tearing up.
In "A Paige From the Past" when Paige goes back in time to see her parents' deaths. That remains Rose McGowan's strongest performance of the series.
The sixth season finale where Chris dies and Leo just loses it does it for me. Cried the first two viewings of this episode.
In "Payback's A Witch," during his birthday party, Wyatt brings his action figures to life to search for the Put on a Bus Leo. Wyatt doesn't know what happened, but he feels Leo broke a promise to always be there. That is sad enough, but it turns out that Wyatt blames himself for Leo going away.

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